Women’s health · Dr. Michele Burklund

Perimenopause.
A new relationship
with your body.

The shifting rhythms. The restless nights. The feeling that something is different. A place to understand this transition, explore the plants, and find your next step.

Plant knowledge. Thoughtful medicine. Your own experience.

The woman within the transition

Your body is changing.
You deserve to understand it.

Perimenopause is the transition leading up to menopause. Changes in your cycle, temperature, sleep, mood, or vaginal comfort can become part of the picture. The experience is different for every woman. [1]

I begin with your story: what has changed, what you need help with, and what you want your life to feel like. Food, movement, rest, botanical medicine, and appropriate medical treatment can each have a place in that conversation.

This page opens one part of that conversation: the relationship between plants and the changing female body.

Ask about personalized care

THE DUTCH TEST

A closer look at your hormone patterns

From my practice · Selected hormone testing

Your hormones.
A deeper conversation.

I use DUTCH hormone testing to explore sex hormones, their metabolites, and cortisol patterns alongside your symptoms, cycle history, sleep, and hormone use.

For the woman asking what is changing, testing can be one part of a thoughtful, individual assessment.

Order the DUTCH test

View the exact panel, current price, collection instructions, and ordering eligibility on Fullscript. Discuss test selection and interpretation with your clinician; this test alone does not diagnose perimenopause.

About DUTCH hormone testing ↗

The botanical field notes

Phytoestrogens.
Seeds, beans & blossoms.

Four plants. Different chemistries.
A more thoughtful way to explore them.

Phytoestrogens are plant compounds that can interact with estrogen receptors. The name describes a chemical relationship; it does not mean that a plant acts exactly like your body’s estrogen or a prescribed hormone.

The particular compound, preparation, dose, and tissue all matter. These plants do not automatically detect and correct a “hormone imbalance.” Their biology is more interesting—and more specific—than that. [2]

Here, I bring together the plants from my Medicine Wild phytoestrogen article, with a closer look at their constituents and their place in everyday life.

01 / Start with nourishment

Food has its own value.

Soy foods and ground flax can bring nourishment to a meal, whether or not they change a menopausal symptom.

02 / Know the preparation

A tea is not an extract.

A cup of blossoms, a spoonful of seed, and an isolated compound deliver different mixtures and amounts.

03 / Keep the question specific

What are we supporting?

A nourishing breakfast, an evening ritual, and treatment for disruptive hot flashes are different goals.

Get to know the plants

A small botanical
companion.

Start with the essentials. Open each field note for a little history, sensory character, and a personal invitation to reflect.

01 / The kitchen ally

Soy

Glycine max

Mild. Savory. Nourishing.

The chemistry
Isoflavones, including genistein, daidzein, and glycitein. These compounds are part of the research on soy and estrogen receptors. [2]
In everyday life
Tofu, tempeh, and cooked edamame make practical starting points. Soy foods contribute protein; calcium content depends on the product and how it is made.
What the research says
Some soy products may modestly reduce hot flashes, but results vary. A food’s nutritional value is a separate question from its ability to treat a symptom. [3]
History, character & a little symbolism

Soy belongs to longstanding East Asian food traditions, expressed through different preparations and fermentation practices.

Its mild flavor makes room for other ingredients. As a personal symbol, it can stand for the ordinary nourishment we return to again and again.

A thoughtful note: Avoid soy with a soy allergy. Concentrated isoflavone supplements need their own review; they are not equivalent to a serving of tofu.

02 / The nourishing thread

Flaxseed

Linum usitatissimum

Nutty. Earthy. A little softness.

The chemistry
Lignans, including secoisolariciresinol diglucoside (SDG). Gut bacteria can convert plant lignans into compounds such as enterodiol and enterolactone. [2]
In everyday life
Food-grade ground flax stirred into cooked porridge brings fiber and alpha-linolenic acid (ALA), a plant omega-3 fat. The seed and its oil offer different nutritional profiles.
What the research says
A controlled trial did not find better hot-flash relief from a flaxseed product than from placebo. Enjoy it as food without expecting it to resolve hormonal symptoms. [2]
History, character & a little symbolism

Flax has supplied both linen fiber and food. Its seed also has a long history in digestive traditions.

For personal reflection, the thread of flax can suggest continuity: what still sustains you while other parts of life are changing.

A thoughtful note: Increase fiber gradually and include fluids. Review supplements and medication timing with your clinician or pharmacist. [4]

03 / The meadow blossom

Red clover

Trifolium pratense

Green. Grassy. Of the meadow.

The chemistry
Isoflavones including formononetin, biochanin A, genistein, and daidzein. Laboratory research helps describe this chemistry; it does not establish a clinical benefit by itself. [5]
In herbal practice
The flowering tops appear in teas and extracts. Tea is a sensory herbal preparation, not a dependable source of dietary protein or minerals. Standardized extracts are a different preparation.
What the research says
Hot-flash studies have had mixed results. Red clover has not been shown conclusively to benefit a health condition, and preparation matters when interpreting a study. [6]
History, character & a little symbolism

Red clover connects meadow herbalism with the modern study of isoflavone-rich preparations. Its familiar blossom invites a closer look at an ordinary field.

As a personal symbol, I offer the image of quiet abundance: something small and beautiful growing close to the ground.

A thoughtful note: Avoid red clover supplements during pregnancy or breastfeeding. Review hormone-sensitive conditions and medications before use.

04 / The evening vine

Hops

Humulus lupulus

Bitter. Aromatic. Resinous.

The chemistry
8-prenylnaringenin (8-PN) is a phytoestrogen studied in hops. The plant also contains related prenylated compounds; one constituent does not describe the whole preparation. [5]
In herbal tradition
The cones, also called strobiles, appear in European preparations for evening rest. The EMA recognizes specified preparations for mild mental stress and sleep on the basis of traditional use. [7]
What the research says
Small trials of standardized extracts have explored menopausal symptoms, with mixed findings. They do not establish that a homemade tea will have the same effect. [8]
History, character & a little symbolism

Known through brewing and evening-rest traditions, hops has a distinctive bitter and aromatic character.

For personal reflection, the vine can represent making room for the day to end. That image is a ritual invitation, not a claim that hops will treat insomnia.

A thoughtful note: Review potential drowsiness, sedating medicines, and hormone-sensitive conditions with your clinician before choosing a hops preparation.

The symbolic meanings here are personal reflections. They are not presented as shared historical beliefs or medical effects.

Begin in the kitchen

Small rituals.
Ordinary nourishment.

Let food be something you enjoy, rather than another protocol to get perfectly right.

01 / A softer morning

Warm porridge & flax.

Stir food-grade ground flax into cooked oats. Add berries and a food you enjoy for protein. Begin with a small amount if fiber is new to your routine.

02 / A substantial lunch

Tempeh, greens & grains.

Pair cooked tempeh with greens, a grain, and a dressing you love. Its place on the plate begins with nourishment and flavor.

03 / An easy addition

A bowl of edamame.

Add cooked, shelled edamame to a soup, salad, or rice bowl. A familiar, repeatable meal can be its own form of care.

Food · Infusion · Extract

The preparation
changes the conversation.

01

On the plate

Whole foods bring a mixture of nutrients and plant compounds. Choose for taste, nourishment, allergies, and your everyday needs.

02

In the cup

Tea draws some constituents into water. Species, plant part, quantity, and brewing time change what ends up in the cup. An extract study does not tell us what a homemade infusion will do.

03

In a concentrated formula

Read the species, plant part, extract, and active-ingredient information. Review it alongside medicines, hormone therapy, and other supplements before deciding whether it belongs in your care.

Make room for your own situation

A plant can be powerful.
The choice should be personal.

Talk with your care team before using concentrated phytoestrogens if you have a hormone-sensitive condition, use endocrine treatment, are pregnant or breastfeeding, or take regular medications. Food and supplements deserve separate conversations. Unexplained bleeding—including any bleeding after menopause—needs medical assessment. [1] [9]

For disruptive hot flashes or other symptoms, discuss the full range of treatment options. Phytoestrogens are not interchangeable with prescribed hormone therapy.

Let’s talk about your care
Selected products from Dr. Michele Burklund’s The Perimenopause Edit, arranged with linen and fresh botanicals
Selected products from my Perimenopause Edit.

Dr. Michele Burklund’s collection

The Perimenopause
Edit.

Thoughtful support for the changing female body.

Perimenopause asks us to pay attention. To the nights that feel different. The shifting rhythms. The woman we are becoming. I begin with nourishment, rest, movement, and listening to the body in front of me.

This is my personal edit of the botanicals and nutritional formulas I consider through a naturopathic and functional medicine lens—with room for strength, pleasure, and feeling at home in yourself.

Explore my Perimenopause Protocol

Open my Fullscript collection. Explore individual products and choose what fits your needs.

Your body is changing.
Your care can evolve with it.

Seven selections in my current collection. Browse the ingredients, product details, and available pricing on Fullscript.

01 / NOURISH

The daily foundation.

A nutritional starting point, chosen around your food, your history, and what you already take.

  • Perimenopause Multi CapsulesNeeded
  • Peri Support PackPerelel

These are different options for a nutritional foundation. Review their overlapping ingredients before choosing.

02 / ENERGY & BONE

Cellular energy. Strong foundations.

I include creatine here for cellular energy and mitochondrial support: it helps replenish ATP, the energy your cells use. Osteo-K is the bone-health selection.

  • Creatine PowderNeeded
  • Osteo-KNBI

03 / FEMININE ECOLOGY

Plants & the inner ecosystem.

Botanical tradition and the microbiome both have a place in my approach to the changing female body.

  • Shatavari ComplexGaia Herbs Pro
  • FemEcologyVitanica

04 / THE INNER LIFE

How you feel matters.

Mood, sleep, and the demands of everyday life deserve their own conversation. This selection belongs within that individual assessment.

  • Serotonin Mood SupportBrainMD

Review this formula’s ingredients and medicine interactions with your clinician before use.

Supplements & labs

Listen first.
Ask better questions.

My functional and naturopathic approach begins with your story. Laboratory testing can be part of a more individual assessment when it answers a useful question about your symptoms, history, or nutritional needs.

Explore the laboratory-testing guidance Discuss your needs in private care

Exclusive access to my Fullscript collection

Explore the edit.
Make it your own.

You can order individual products. Take your time with the ingredients, ask questions, and choose only what is appropriate for you.

  1. 01Open the collection

    See the products selected for this edit.

  2. 02Read & choose

    Compare ingredients, directions, and current pricing.

  3. 03Order through Fullscript

    Sign in or create an account to complete your purchase.

Shop the Perimenopause Edit

For help choosing products or doses, explore private care.

Your story comes first

Testing with
a clear purpose.

Your symptoms and menstrual history are central to understanding the transition. Testing is considered when it can help answer a particular question; you do not need to order a large hormone panel to begin a conversation.

Explore the tests I have selected, then discuss which—if any—would change your care.

Shop the tests I use in practice

A little more clarity

Your questions,
answered.

Will phytoestrogens balance my hormones?

They can interact with estrogen receptors, but they do not act as an automatic balancing system. The preparation, your health history, and the symptom being addressed all matter.

Are soy foods and isoflavone supplements the same?

No. Soy foods provide a mixture of nutrients and constituents. A concentrated supplement may deliver a very different amount and mixture of isoflavones. Evaluate those choices separately.

Can these plants help with hot flashes?

Some soy preparations may offer a small benefit, but findings are inconsistent. Red clover and hops studies also have limitations. The Menopause Society’s 2023 statement does not recommend supplements or soy products as reliable treatments for hot flashes. That does not remove the nutritional value of soy foods. [10]

Do I have to take supplements to begin?

No. You can start with food, an assessment of your symptoms, and a conversation about sleep, movement, and what feels manageable. My free Foundations course is another place to begin.

Can I combine these plants with hormone therapy?

Do not assume a concentrated botanical or isoflavone product is compatible with your treatment. Review the exact ingredients and dose with your prescriber or pharmacist. Ordinary foods are a separate conversation.

The wider conversation

Your next chapter.
More room to explore.

For the curious

Sources & further reading.

Adapted and expanded from my Medicine Wild article, with the references below for clinical context.

  1. National Institute on Aging · What Is Menopause?
  2. National Cancer Institute · Hot Flashes and Night Sweats (PDQ)
  3. NCCIH · Soy
  4. NCCIH · Flaxseed and Flaxseed Oil
  5. Overk et al. · Hops and red clover chemistry, laboratory study (2005)
  6. NCCIH · Red Clover
  7. European Medicines Agency · Hop strobile
  8. Erkkola et al. · Standardized hops extract, randomized pilot trial (2010)
  9. NCCIH · Menopausal Symptoms and Complementary Approaches
  10. The Menopause Society · 2023 Nonhormone Therapy Position Statement

Your next step